The role of Src & ERK1/2 kinases in inspiratory resistive breathing induced acute lung injury and inflammation

BACKGROUND: Inspiratory resistive breathing (IRB), a hallmark of obstructive airway diseases, is associated with large negative intrathoracic pressures, due to strenuous contractions of the inspiratory muscles. IRB is shown to induce lung injury in previously healthy animals. Src is a multifunctiona...

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Vydáno v:Respir Res
Hlavní autoři: Toumpanakis, Dimitrios, Vassilakopoulou, Vyronia, Sigala, Ioanna, Zacharatos, Panagiotis, Vraila, Ioanna, Karavana, Vassiliki, Theocharis, Stamatios, Vassilakopoulos, Theodoros
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729404/
https://ncbi.nlm.nih.gov/pubmed/29237457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0694-7
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