Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004

We conducted a cytogenetic analysis of 642 children with de novo acute myeloid leukemia (AML) treated on the AML-Berlin-Frankfurt-Münster (BFM) 04 protocol to determine the prognostic value of specific chromosomal aberrations including monosomal (MK(+)), complex (CK(+)) and hypodiploid (HK(+)) karyo...

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Pubblicato in:Leukemia
Autori principali: Rasche, M, von Neuhoff, C, Dworzak, M, Bourquin, J-P, Bradtke, J, Göhring, G, Escherich, G, Fleischhack, G, Graf, N, Gruhn, B, Haas, O A, Klingebiel, T, Kremens, B, Lehrnbecher, T, von Stackelberg, A, Tchinda, J, Zemanova, Z, Thiede, C, von Neuhoff, N, Zimmermann, M, Creutzig, U, Reinhardt, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729330/
https://ncbi.nlm.nih.gov/pubmed/28443606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.121
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