Molecular cloning and characterization of the family of feline leucine-rich glioma-inactivated (LGI) genes, and mutational analysis in familial spontaneous epileptic cats

BACKGROUND: Leucine-rich glioma-inactivated (LGI) proteins play a critical role in synaptic transmission. Dysfunction of these genes and encoded proteins is associated with neurological disorders such as genetic epilepsy or autoimmune limbic encephalitis in animals and human. Familial spontaneous ep...

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Vydáno v:BMC Vet Res
Hlavní autoři: Yu, Yoshihiko, Hasegawa, Daisuke, Fujiwara-Igarashi, Aki, Hamamoto, Yuji, Mizoguchi, Shunta, Kuwabara, Takayuki, Fujita, Michio
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729232/
https://ncbi.nlm.nih.gov/pubmed/29237452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-017-1308-9
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