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DDM1 and Lsh remodelers allow methylation of DNA wrapped in nucleosomes

Cytosine methylation regulates essential genome functions across eukaryotes, but the fundamental question of whether nucleosomal or naked DNA is the preferred substrate of plant and animal methyltransferases remains unresolved. Here, we show that genetic inactivation of a single DDM1/Lsh family nucl...

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Pubblicato in:eLife
Autori principali: Lyons, David B, Zilberman, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728721/
https://ncbi.nlm.nih.gov/pubmed/29140247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30674
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