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Extracting a biologically relevant latent space from cancer transcriptomes with variational autoencoders

The Cancer Genome Atlas (TCGA) has profiled over 10,000 tumors across 33 different cancer-types for many genomic features, including gene expression levels. Gene expression measurements capture substantial information about the state of each tumor. Certain classes of deep neural network models are c...

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Bibliografske podrobnosti
izdano v:Pac Symp Biocomput
Main Authors: Way, Gregory P., Greene, Casey S.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728678/
https://ncbi.nlm.nih.gov/pubmed/29218871
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