Cytogenetics-based risk prediction of blastic transformation of chronic myeloid leukemia in the era of TKI therapy

The high fatality of patients with blast phase (BP) chronic myeloid leukemia (CML) necessitates identification of high-risk (HR) patients to prevent onset of BP. Here, we investigated the risk of BP based on additional chromosomal abnormality (ACA) profiles in a cohort of 2326 CML patients treated w...

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Gong, Zimu, Medeiros, L. Jeffrey, Cortes, Jorge E., Chen, Zi, Zheng, Lan, Li, Yan, Bai, Shi, Lin, Pei, Miranda, Roberto N., Jorgensen, Jeffrey L., McDonnell, Timothy J., Wang, Wei, Kantarjian, Hagop M., Hu, Shimin
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Myeloid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728641/
https://ncbi.nlm.nih.gov/pubmed/29296906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011858
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