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Interleukin-35 mitigates the function of murine transplanted islet cells via regulation of Treg/Th17 ratio
Pancreatic islet transplantation is a promising treatment for type 1 diabetes (T1D). Interleukin-35 (IL-35) is a recently discovered cytokine that exhibits potent immunosuppressive functions. However, the role of IL-35 in islet transplant rejection remains to be elucidated. In this study, we isolate...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728515/ https://ncbi.nlm.nih.gov/pubmed/29236782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189617 |
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