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The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels

Coordinating angiogenesis with acquisition of tissue-specific properties in endothelial cells is essential for vascular function. In the retina, endothelial cells form a blood-retina barrier by virtue of tight junctions and low transcytosis. While the canonical Norrin/Fz4/Lrp5/6 pathway is essential...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Mazzoni, Jenna, Smith, Julian R., Shahriar, Sanjid, Cutforth, Tyler, Ceja, Bernardo, Agalliu, Dritan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728434/
https://ncbi.nlm.nih.gov/pubmed/29154126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.10.025
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