The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain

Some viruses use phosphatidylinositol phosphate (PIP) to mark membranes used for genome replication or virion assembly. PIP-binding motifs of cellular proteins do not exist in viral proteins. Molecular-docking simulations revealed a putative site of PIP binding to poliovirus (PV) 3C protein that was...

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Publicado en:Structure
Main Authors: Shengjuler, Djoshkun, Chan, Yan Mei, Sun, Simou, Moustafa, Ibrahim M., Li, Zhen-Lu, Gohara, David W., Buck, Matthias, Cremer, Paul S., Boehr, David D., Cameron, Craig E.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Ltd. 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728361/
https://ncbi.nlm.nih.gov/pubmed/29211985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.11.001
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