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Convection shapes the trade-off between antibiotic efficacy and the selection for resistance in spatial gradients

Since penicillin was discovered about 90 years ago, we have become used to using drugs to eradicate unwanted pathogenic cells. However, using drugs to kill bacteria, viruses or cancer cells has the serious side effect of selecting for mutant types that survive the drug attack. A key question therefo...

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Publicado en:Phys Biol
Main Authors: Gralka, Matti, Fusco, Diana, Martis, Stephen, Hallatschek, Oskar
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728155/
https://ncbi.nlm.nih.gov/pubmed/28649977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/aa7bb3
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