The gene–treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry

BACKGROUND: Although statins deteriorate glucose metabolism, their glucose-lowering effects have emerged in some situations. Here, we assessed whether these effects are a consequence of statins’ interaction with paraoxonase (PON)1 enzyme polymorphism. METHODS: Adult Japanese type 2 diabetes patients...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Sumi, Akiko, Nakamura, Udai, Iwase, Masanori, Fujii, Hiroki, Ohkuma, Toshiaki, Ide, Hitoshi, Jodai-Kitamura, Tamaki, Komorita, Yuji, Yoshinari, Masahito, Hirakawa, Yoichiro, Hirano, Atsushi, Kubo, Michiaki, Kitazono, Takanari
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728066/
https://ncbi.nlm.nih.gov/pubmed/29233102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-017-0509-1
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