Th17 immune microenvironment in Epstein-Barr virus–negative Hodgkin lymphoma: implications for immunotherapy

Classical Hodgkin lymphoma (CHL) is a neoplasm characterized by robust inflammatory infiltrates and heightened expression of the immunosuppressive PD-1/PD-L1 pathway. Although anti-PD-1 therapy can be effective in >60% of patients with refractory CHL, improved treatment options are needed for CHL...

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Publicado en:Blood Adv
Autores principales: Duffield, Amy S., Ascierto, Maria Libera, Anders, Robert A., Taube, Janis M., Meeker, Alan K., Chen, Shuming, McMiller, Tracee L., Phillips, Neil A., Xu, Haiying, Ogurtsova, Aleksandra, Berger, Alan E., Pardoll, Drew M., Topalian, Suzanne L., Ambinder, Richard F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2017
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727974/
https://ncbi.nlm.nih.gov/pubmed/29296775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007260
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