Th17 immune microenvironment in Epstein-Barr virus–negative Hodgkin lymphoma: implications for immunotherapy

Classical Hodgkin lymphoma (CHL) is a neoplasm characterized by robust inflammatory infiltrates and heightened expression of the immunosuppressive PD-1/PD-L1 pathway. Although anti-PD-1 therapy can be effective in >60% of patients with refractory CHL, improved treatment options are needed for CHL...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Duffield, Amy S., Ascierto, Maria Libera, Anders, Robert A., Taube, Janis M., Meeker, Alan K., Chen, Shuming, McMiller, Tracee L., Phillips, Neil A., Xu, Haiying, Ogurtsova, Aleksandra, Berger, Alan E., Pardoll, Drew M., Topalian, Suzanne L., Ambinder, Richard F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727974/
https://ncbi.nlm.nih.gov/pubmed/29296775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007260
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