An influenza A virus (H7N9) anti-neuraminidase monoclonal antibody protects mice from morbidity without interfering with the development of protective immunity to subsequent homologous challenge

The emergence of A(H7N9) virus strains with resistance to neuraminidase (NA) inhibitors highlights a critical need to discover new countermeasures for treatment of A(H7N9) virus-infected patients. We previously described an anti-NA mAb (3c10-3) that has prophylactic and therapeutic efficacy in mice...

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Bibliografski detalji
Izdano u:Virology
Glavni autori: Wilson, Jason R., Belser, Jessica A., DaSilva, Juliana, Guo, Zhu, Sun, Xiangjie, Gansebom, Shane, Bai, Yaohui, Stark, Thomas J., Chang, Jessie, Carney, Paul, Levine, Min Z., Barnes, John, Stevens, James, Maines, Taronna R., Tumpey, Terrence M., York, Ian A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727915/
https://ncbi.nlm.nih.gov/pubmed/28888111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.08.016
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