Whole-exome sequencing for RH genotyping and alloimmunization risk in children with sickle cell anemia

RH genes are highly polymorphic and encode the most complex of the 35 human blood group systems. This genetic diversity contributes to Rh alloimmunization in patients with sickle cell anemia (SCA) and is not avoided by serologic Rh-matched red cell transfusions. Standard serologic testing does not d...

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Chou, Stella T., Flanagan, Jonathan M., Vege, Sunitha, Luban, Naomi L. C., Brown, R. Clark, Ware, Russell E., Westhoff, Connie M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2017
Schlagworte:
Transfusion Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727856/
https://ncbi.nlm.nih.gov/pubmed/29296782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007898
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