High proportions of PD-1(+) and PD-L1(+) leukocytes in classical Hodgkin lymphoma microenvironment are associated with inferior outcome

Immune checkpoint inhibition targeting the programmed death receptor (PD)-1 pathway is a novel treatment approach in relapsed and refractory classical Hodgkin lymphoma (cHL). Identifying patients with a high risk of treatment failure could support the use of PD-1 inhibitors as front-line treatment....

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Hollander, Peter, Kamper, Peter, Smedby, Karin Ekstrom, Enblad, Gunilla, Ludvigsen, Maja, Mortensen, Julie, Amini, Rose-Marie, Hamilton-Dutoit, Stephen, d’Amore, Francesco, Molin, Daniel, Glimelius, Ingrid
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2017
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727849/
https://ncbi.nlm.nih.gov/pubmed/29296784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006346
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