Gene Expression Changes in Long-Term In Vitro Human Blood-Brain Barrier Models and Their Dependence on a Transwell Scaffold Material

Disruption of the blood-brain barrier (BBB) is the hallmark of many neurovascular disorders, making it a critically important focus for therapeutic options. However, testing the effects of either drugs or pathological agents is difficult due to the potentially damaging consequences of altering the n...

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Publicado en:J Healthc Eng
Autores principales: Gaston, Joel D., Bischel, Lauren L., Fitzgerald, Lisa A., Cusick, Kathleen D., Ringeisen, Bradley R., Pirlo, Russell K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727720/
https://ncbi.nlm.nih.gov/pubmed/29317995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5740975
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