POLE somatic mutations in advanced colorectal cancer

Despite all the knowledge already gathered, the picture of somatic genetic changes in colorectal tumorigenesis is far from complete. Recently, germline and somatic mutations in the exonuclease domain of polymerase epsilon, catalytic subunit (POLE) gene have been reported in a small subset of microsa...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Guerra, Joana, Pinto, Carla, Pinto, Diana, Pinheiro, Manuela, Silva, Romina, Peixoto, Ana, Rocha, Patrícia, Veiga, Isabel, Santos, Catarina, Santos, Rui, Cabreira, Verónica, Lopes, Paula, Henrique, Rui, Teixeira, Manuel R.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727326/
https://ncbi.nlm.nih.gov/pubmed/29072370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1245
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