POLE somatic mutations in advanced colorectal cancer

Despite all the knowledge already gathered, the picture of somatic genetic changes in colorectal tumorigenesis is far from complete. Recently, germline and somatic mutations in the exonuclease domain of polymerase epsilon, catalytic subunit (POLE) gene have been reported in a small subset of microsa...

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Bibliografski detalji
Izdano u:Cancer Med
Glavni autori: Guerra, Joana, Pinto, Carla, Pinto, Diana, Pinheiro, Manuela, Silva, Romina, Peixoto, Ana, Rocha, Patrícia, Veiga, Isabel, Santos, Catarina, Santos, Rui, Cabreira, Verónica, Lopes, Paula, Henrique, Rui, Teixeira, Manuel R.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Cancer Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727326/
https://ncbi.nlm.nih.gov/pubmed/29072370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1245
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