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Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease
The transcription factor BMAL1 is a core component of the molecular clock, regulating biological pathways that drive 24 h (circadian) rhythms in behaviour and physiology. The molecular clock has a profound influence on innate immune function, and circadian disruption is linked with increased inciden...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727202/ https://ncbi.nlm.nih.gov/pubmed/29234010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02111-0 |
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