Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference

Cannabinoid CB2 receptors (CB2Rs) are expressed in mouse brain dopamine (DA) neurons and are involved in several DA-related disorders. However, the cell type-specific mechanisms are unclear since the CB2R gene knockout mice are constitutive gene knockout. Therefore, we generated Cnr2-floxed mice tha...

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Publié dans:Sci Rep
Auteurs principaux: Liu, Qing-Rong, Canseco-Alba, Ana, Zhang, Hai-Ying, Tagliaferro, Patricia, Chung, Monika, Dennis, Eugene, Sanabria, Branden, Schanz, Norman, Escosteguy-Neto, Joao Carlos, Ishiguro, Hiroki, Lin, Zhicheng, Sgro, Susan, Leonard, Claire M., Santos-Junior, Jair Guilherme, Gardner, Eliot L., Egan, Josephine M., Lee, Jeung Woon, Xi, Zheng-Xiong, Onaivi, Emmanuel S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727179/
https://ncbi.nlm.nih.gov/pubmed/29234141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17796-y
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