Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

Type II CRISPR-Cas systems introduce double-strand breaks into DNA of invading genetic material and use DNA fragments to acquire novel spacers during adaptation. These breaks can be the substrate of several DNA repair pathways, paving the way for interactions. We report that non-homologous end-joini...

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發表在:Nat Commun
Main Authors: Bernheim, Aude, Calvo-Villamañán, Alicia, Basier, Clovis, Cui, Lun, Rocha, Eduardo P. C., Touchon, Marie, Bikard, David
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727150/
https://ncbi.nlm.nih.gov/pubmed/29234047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02350-1
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