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Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

Type II CRISPR-Cas systems introduce double-strand breaks into DNA of invading genetic material and use DNA fragments to acquire novel spacers during adaptation. These breaks can be the substrate of several DNA repair pathways, paving the way for interactions. We report that non-homologous end-joini...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Bernheim, Aude, Calvo-Villamañán, Alicia, Basier, Clovis, Cui, Lun, Rocha, Eduardo P. C., Touchon, Marie, Bikard, David
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727150/
https://ncbi.nlm.nih.gov/pubmed/29234047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02350-1
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