Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment

The current study employed next-generation RNA sequencing to examine gene expression differences related to brain aging, cognitive decline, and hippocampal subfields. Young and aged rats were trained on a spatial episodic memory task. Hippocampal regions CA1, CA3, and the dentate gyrus were isolated...

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Bibliografiske detaljer
Udgivet i:Front Aging Neurosci
Main Authors: Ianov, Lara, De Both, Matt, Chawla, Monica K., Rani, Asha, Kennedy, Andrew J., Piras, Ignazio, Day, Jeremy J., Siniard, Ashley, Kumar, Ashok, Sweatt, J. David, Barnes, Carol A., Huentelman, Matthew J., Foster, Thomas C.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727020/
https://ncbi.nlm.nih.gov/pubmed/29276487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00383
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