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BoBER: web interface to the base of bioisosterically exchangeable replacements

We describe a novel freely available web server Base of Bioisosterically Exchangeable Replacements (BoBER), which implements an interface to a database of bioisosteric and scaffold hopping replacements. Bioisosterism and scaffold hopping are key concepts in drug design and optimization, and can be d...

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Detalhes bibliográficos
Publicado no:J Cheminform
Main Authors: Lešnik, Samo, Škrlj, Blaž, Eržen, Nika, Bren, Urban, Gobec, Stanislav, Konc, Janez, Janežič, Dušanka
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727005/
https://ncbi.nlm.nih.gov/pubmed/29234984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-017-0251-x
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