Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer

Cancer is a heterogeneous disease harboring diverse subclonal populations that can be discriminated by their DNA mutations. Environmental pressure selects subclones that ultimately drive disease progression and tumor relapse. Circulating cell-free DNA (ccfDNA) can be used to approximate the mutation...

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Vydáno v:Cancer Genet
Hlavní autoři: Vietsch, Eveline E, Graham, Garrett T, McCutcheon, Justine N, Javaid, Aamir, Giaccone, Giuseppe, Marshall, John L, Wellstein, Anton
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726797/
https://ncbi.nlm.nih.gov/pubmed/29153095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2017.08.006
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