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Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis

Neprilysin (NEP, CD10) acts to limit excessive inflammation partly by hydrolyzing neuropeptides. Although deletion of NEP exacerbates intestinal inflammation in animal models, its role in ulcerative colitis (UC) is not well explored. Herein, we aimed to demonstrate changes in NEP and associated neur...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sargın, Zeynep Gök, Erin, Nuray, Tazegul, Gokhan, Elpek, Gülsüm Özlem, Yıldırım, Bülent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726735/
https://ncbi.nlm.nih.gov/pubmed/29232715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189526
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