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Inhibition of CD147 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation

BACKGROUND AND PURPOSE: Inflammation and thrombosis currently are recognized as critical contributors to the pathogenesis of ischemic stroke. CD147, also known as extracellular matrix metalloproteinase inducer, can function as a key mediator of inflammatory and immune responses. CD147 expression is...

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Vydáno v:Stroke
Hlavní autoři: Jin, Rong, Xiao, Adam Y, Chen, Rui, Granger, D. Neil, Li, Guohong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726599/
https://ncbi.nlm.nih.gov/pubmed/29114092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.018839
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