Eplerenone Reduces Atrial Fibrillation Burden Without Preventing Atrial Electrical Remodeling

BACKGROUND: The aldosterone inhibitor eplerenone (EPL) has been shown to reduce the incidence of AF in patients with systolic heart failure, but the mechanism is unknown. OBJECTIVES: We hypothesized that by reducing atrial dilatation and fibrosis in the absence of heart failure EPL also reduces AF b...

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Detalhes bibliográficos
Publicado no:J Am Coll Cardiol
Main Authors: Takemoto, Yoshio, Ramirez, Rafael J., Kaur, Kuljeet, Salvador-Montañés, Oscar, Ponce-Balbuena, Daniela, Ramos-Mondragón, Roberto, Ennis, Steven R., Guerrero-Serna, Guadalupe, Berenfeld, Omer, Jalife, José
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726581/
https://ncbi.nlm.nih.gov/pubmed/29216985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2017.10.014
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