Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior

Haploinsufficiency of the AT-rich interactive domain 1B (ARID1B) gene causes autism spectrum disorder (ASD) and intellectual disability, however, the neurobiological basis for this is unknown. Here, we generated Arid1b knockout mice and examined heterozygotes to model human patients. Arid1b heterozy...

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Publicat a:Nat Neurosci
Autors principals: Jung, Eui-Man, Moffat, Jeffrey Jay, Liu, Jinxu, Dravid, Shashank Manohar, Gurumurthy, Channabasavaiah, Kim, Woo-Yang
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726525/
https://ncbi.nlm.nih.gov/pubmed/29184203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-017-0013-0
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