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In-gene Quantification of O(6)-Methylguanine with Elongated Nucleoside Analogues on Gold Nanoprobes
Exposure of DNA to chemicals can result in the formation of DNA adducts, a molecular initiating event in genotoxin-induced carcinogenesis. O(6)-Methylguanine (O(6)-MeG) is a highly mutagenic DNA adduct that forms in human genomic DNA upon reaction with methylating agents of dietary, environmental, o...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5726487/ https://ncbi.nlm.nih.gov/pubmed/27314828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03599 |
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