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5-HT(2) Receptor Activation Facilitates a Persistent Sodium Current and Repetitive Firing in Spinal Motoneurons of Rats With and Without Chronic Spinal Cord Injury

We examined the modulation of persistent inward currents (PICs) by serotonin (5-HT) in spinal motoneurons of normal and chronic spinal rats. PICs are composed of both a TTX-sensitive persistent sodium current (Na PIC) and a nimodipine-sensitive persistent calcium current (Ca PIC), and we focused on...

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Vydáno v:J Neurophysiol
Hlavní autoři: Harvey, P. J., Li, X., Li, Y., Bennett, D. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726401/
https://ncbi.nlm.nih.gov/pubmed/16707714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01088.2005
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