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Understanding and Interrupting the Fischer Azaindolization Reaction

Experimental and computational studies pertaining to the Fischer azaindolization reaction are reported. These studies explain why pyridylhydrazines are poorly reactive in Fischer indolization reactions, in addition to the origin of hydrazine substituent effects. Additionally, an interrupted variant...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Simmons, Bryan J., Hoffmann, Marie, Champagne, Pier Alexandre, Picazo, Elias, Yamakawa, Katsuya, Morrill, Lucas A., Houk, K. N., Garg, Neil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726400/
https://ncbi.nlm.nih.gov/pubmed/29022706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07518
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