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The clinicopathological significance of HES1 promoter hypomethylation in patients with colorectal cancer
Hairy/enhancer of split 1 (HES1) is a basic helix–loop–helix transcriptional repressor. Aberrant demethylation has been considered a common mechanism of tumor promoter gene activation. In the current study, we aimed to investigate the methylation status of the HES1 promoter and correlations with cli...
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| 出版年: | Onco Targets Ther |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5726367/ https://ncbi.nlm.nih.gov/pubmed/29263679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S151857 |
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