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Dissecting cellular senescence and SASP in Drosophila

Cellular senescence can act as both tumor suppressor and tumor promoter depending on the cellular contexts. On one hand, premature senescence has been considered as an innate host defense mechanism against carcinogenesis in mammals. In response to various stresses including oxidative stress, DNA dam...

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Bibliographic Details
Published in:Inflamm Regen
Main Authors: Ito, Takao, Igaki, Tatsushi
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725765/
https://ncbi.nlm.nih.gov/pubmed/29259698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-016-0031-4
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