Tranylcypromine Causes Neurotoxicity and Represses BHC110/LSD1 in Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids Model

Recent breakthroughs in human pluripotent stem cell-derived cerebral organoids provide a valuable platform for investigating the human brain after different drugs treatments and for understanding the complex genetic background to human pathology. Here, we identified tranylcypromine, which is used to...

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Dades bibliogràfiques
Publicat a:Front Neurol
Autors principals: Huang, Jing, Liu, Fangkun, Tang, Hui, Wu, Haishan, Li, Lehua, Wu, Renrong, Zhao, Jingping, Wu, Ying, Liu, Zhixiong, Chen, Jindong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725435/
https://ncbi.nlm.nih.gov/pubmed/29270148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00626
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