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Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function

ALDH16A1 is a novel member of the ALDH superfamily that is enzymatically-inactive and highly expressed in the kidney. Recent studies identified an association between a rare missense single nucleotide variant (SNV) in the ALDH16A1 gene and elevated serum uric acid levels and gout. The present study...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Charkoftaki, Georgia, Chen, Ying, Han, Ming, Sandoval, Monica, Yu, Xiaoqing, Zhao, Hongyu, Orlicky, David J., Thompson, David C., Vasiliou, Vasilis
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725231/
https://ncbi.nlm.nih.gov/pubmed/28254523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2017.02.013
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