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Synthesis of methylprednisolone loaded ibuprofen modified dextran based nanoparticles and their application for drug delivery in acute spinal cord injury

To improve the therapeutic efficacy of spinal cord injury (SCI), the methylprednisolone was incorporated into nanoparticles based on the ibuprofen modified dextran. The ibuprofen modified dextran was synthesized using a direct esterification linkage between the carboxylic acids of hydrophobic drug a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qi, Lei, Jiang, Haiyan, Cui, Xiaohui, Liang, Guiwen, Gao, Ming, Huang, Zhongwei, Xi, Qinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725123/
https://ncbi.nlm.nih.gov/pubmed/29245932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20649
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