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The quinone-based derivative, HMNQ induces apoptotic and autophagic cell death by modulating reactive oxygen species in cancer cells

8-Hydroxy-2-methoxy-1,4-naphthoquinone (HMNQ), a natural compound isolated from the bark of Juglans sinensis Dode, displays cytotoxic activity against various human cancer cells. However, the molecular mechanism of the anticancer effect is unclear. In this study, we examined the cytotoxic mechanism...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Lee, Eun Byul, Cheon, Min Gyeong, Cui, Jun, Lee, Yoo Jin, Seo, Eun Kyoung, Jang, Ho Hee
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725121/
https://ncbi.nlm.nih.gov/pubmed/29245930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21005
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