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Transcriptional profiling of PBMCs unravels B cell mediated immunopathogenic imprints of HCV vasculitis

B cell depletion therapy using rituximab has been shown to be effective in achieving remission in patients with HCV-mixed cryoglobulinemic (MC) vasculitis. Previously, we have demonstrated abnormalities in peripheral immune cells involving neutrophils, chemotaxis, and innate immune activation among...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Comstock, Emily, Kim, Cheol-Woo, Murphy, Alison, Emmanuel, Benjamin, Zhang, Xi, Sneller, Michael, Poonia, Bhawna, Kottilil, Shyamasundaran
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724854/
https://ncbi.nlm.nih.gov/pubmed/29228031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188314
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