Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetes

AIMS/HYPOTHESIS: Failure in glucose response to insulin is a common pathology associated with obesity. In this study, we analyzed the genome wide DNA methylation profile of visceral adipose tissue (VAT) samples in a population of individuals with obesity and assessed whether differential methylation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rodríguez-Rodero, Sandra, Menéndez-Torre, Edelmiro, Fernández-Bayón, Gustavo, Morales-Sánchez, Paula, Sanz, Lourdes, Turienzo, Estrella, González, Juan José, Martinez-Faedo, Ceferino, Suarez-Gutiérrez, Lorena, Ares, Jessica, Díaz-Naya, Lucia, Martin-Nieto, Alicia, Fernández-Morera, Juan L., Fraga, Mario F., Delgado-Álvarez, Elías
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724849/
https://ncbi.nlm.nih.gov/pubmed/29228058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189153
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