MicroRNA regulation of nAChR expression and nicotine-dependent behavior in C. elegans

Chronic exposure to nicotine up-regulates nicotinic acetylcholine receptors (nAChRs), and such up-regulation is critical for the development of nicotine dependence in humans and animal models. However, how nicotine up-regulates nAChRs is not well understood. Here we identify a key role for microRNA...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Rauthan, Manish, Gong, Jianke, Liu, Jinzhi, Li, Zhaoyu, Wescott, Seth A., Liu, Jianfeng, Xu, X.Z. Shawn
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724378/
https://ncbi.nlm.nih.gov/pubmed/29117550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.043
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