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Ion Mobility-Mass Spectrometry Reveals a Dipeptide That Acts as a Molecular Chaperone for Amyloid β

Previously, we discovered and structurally characterized a complex between amyloid β 1–40 and the neuropeptide leucine enkephalin. This work identified leucine enkephalin as a potentially useful starting point for the discovery of peptide-related biotherapeutics for Alzheimer’s disease. In order to...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Soper-Hopper, Molly T., Eschweiler, Joseph D., Ruotolo, Brandon T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724361/
https://ncbi.nlm.nih.gov/pubmed/28240851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00045
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