Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer

Proinflammatory signaling pathways are commonly up-regulated in breast cancer. In estrogen receptor-negative (ER(−)) and triple-negative breast cancer (TNBC), nitric oxide synthase-2 (NOS2) and cyclooxygenase-2 (COX2) have been described as independent predictors of disease outcome. We further explo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Basudhar, Debashree, Glynn, Sharon A., Greer, Madison, Somasundaram, Veena, No, Jae Hong, Scheiblin, David A., Garrido, Pablo, Heinz, William F., Ryan, Aideen E., Weiss, Jonathan M., Cheng, Robert Y. S., Ridnour, Lisa A., Lockett, Stephen J., McVicar, Daniel W., Ambs, Stefan, Wink, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724261/
https://ncbi.nlm.nih.gov/pubmed/29087320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1709119114
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