Calmodulin regulates Ca(v)3 T-type channels at their gating brake

Calcium (Ca(v)1 and Ca(v)2) and sodium channels possess homologous CaM-binding motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a universal calcium sensor. Ca(v)3 T-type channels, which serve as pacemakers of the mammalian brain and heart, lack a C-terminal IQ mo...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Chemin, Jean, Taiakina, Valentina, Monteil, Arnaud, Piazza, Michael, Guan, Wendy, Stephens, Robert F., Kitmitto, Ashraf, Pang, Zhiping P., Dolphin, Annette C., Perez-Reyes, Edward, Dieckmann, Thorsten, Guillemette, Joseph Guy, Spafford, J. David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723990/
https://ncbi.nlm.nih.gov/pubmed/28972185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807925
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