Apoptotic Protease Activating Factor-1 Inhibitor Mitigates Myocardial Ischemia Injury via Disturbing Procaspase-9 Recruitment by Apaf-1

(2S,3S,4S,5R,6R)-6-(4-((4-guanidinobutoxy)carbonyl)-2,6-dihydroxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid (ZYZ-488) was discovered as a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1). In present work, a surface plasmon resonance (SPR) assay confirms the dire...

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Опубликовано в: :Oxid Med Cell Longev
Главные авторы: Wang, Ying, Zhang, Qiuyan, Zhong, Liangjie, Lin, Mingshen, Luo, Xiaoling, Liu, Siyu, Xu, Peng, Liu, Xinhua, Zhu, Yi Zhun
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723966/
https://ncbi.nlm.nih.gov/pubmed/29279737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9747296
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