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COMT Val(158)Met Polymorphism Exerts Sex-Dependent Effects on fMRI Measures of Brain Function
Evidence suggests that dopamine levels in the prefrontal cortex (PFC) modulate executive functions. A key regulator of PFC dopamine is catechol-O-methyltransferase (COMT). The activity level of the COMT enzyme are influenced by sex and the Val(158)Met polymorphism (rs4680) of the COMT gene, with mal...
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| Publicado no: | Front Hum Neurosci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5723646/ https://ncbi.nlm.nih.gov/pubmed/29270116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2017.00578 |
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