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Suitability of various chromatographic and spectroscopic techniques for analysis and kinetic degradation study of trelagliptin

Multifaceted comparative analytical methods for trelagliptin (TRL) were investigated, applied to ZAFATEK tablets and HPLC-UV was selected for a degradation kinetic study. UPLC-MS/MS (Method I), UPLC-UV (Method II), HPLC-UV (Method III), UHPLC-UV (Method IV) and direct UV (Method V) methods were deve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zaghary, Wafaa A., Mowaka, Shereen, Hassan, Mostafa A., Ayoub, Bassam M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722889/
https://ncbi.nlm.nih.gov/pubmed/29222475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17642-1
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