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Sphingosine 1-Phosphate Receptor Modulators for the Treatment of Multiple Sclerosis

Sphingosine 1-phosphate receptor (S1PR) modulators possess a unique mechanism of action in the treatment of multiple sclerosis (MS). Subtype 1 of the S1PR is expressed on the surface of lymphocytes and is important in regulating egression from lymph nodes. The S1PR modulators indirectly antagonize t...

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Pubblicato in:Neurotherapeutics
Autori principali: Chaudhry, Burhan Z., Cohen, Jeffrey A., Conway, Devon S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722770/
https://ncbi.nlm.nih.gov/pubmed/28812220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-017-0565-4
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