Clinical and Histopathological Amelioration of Experimental Autoimmune Encephalomyelitis by AAV Vectors Expressing a Soluble Interleukin-23 Receptor

The role of the T helper (Th)17 pathway has been clearly demonstrated in the onset and progression of autoimmune diseases, where interleukin (IL)-23 is a key molecule in maintaining the response mediated by Th17 cells. As a consequence, recent strategies based on blocking the interaction between IL-...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Miralles, Marta, Eixarch, Herena, Tejero, Marcos, Costa, Carme, Hirota, Keiji, Castaño, A. Raul, Puig, Meritxell, Stockinger, Gitta, Montalban, Xavier, Bosch, Assumpció, Espejo, Carmen, Chillon, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722756/
https://ncbi.nlm.nih.gov/pubmed/28593439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-017-0545-8
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