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Soluble PD-1 and PD-L1: predictive and prognostic significance in cancer
The membrane-bound molecules programmed death 1 (PD-1) and its ligand PD-L1 (PD-1/PD-L1) belong to the immune checkpoint pathway. PD-1 pathway downregulates effector T cells in immune response, thereby causing immune suppression. Recent studies have revealed that membrane-bound PD-1 and PD-L1 also h...
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| Pubblicato in: | Oncotarget |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5722594/ https://ncbi.nlm.nih.gov/pubmed/29228642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18311 |
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