Excessively low salt diet damages the heart through activation of cardiac (pro) renin receptor, renin-angiotensin-aldosterone, and sympatho-adrenal systems in spontaneously hypertensive rats

OBJECTIVE: A high salt intake causes hypertension and leads to cardiovascular disease. Therefore, a low salt diet is now recommended to prevent hypertension and cardiovascular disease. However, it is still unknown whether an excessively low salt diet is beneficial or harmful for the heart. METHODS:...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Okamoto, Chihiro, Hayakawa, Yuka, Aoyama, Takuma, Komaki, Hisaaki, Minatoguchi, Shingo, Iwasa, Masamitsu, Yamada, Yoshihisa, Kanamori, Hiromitsu, Kawasaki, Masanori, Nishigaki, Kazuhiko, Mikami, Atsushi, Minatoguchi, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722333/
https://ncbi.nlm.nih.gov/pubmed/29220406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189099
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