Cortical β-Amyloid Burden, Gray Matter, and Memory in Adults at Varying APOE ε4 Risk for Alzheimer’s Disease

Models of preclinical Alzheimer’s disease (AD) propose that cerebral amyloidosis leads to neurodegeneration and subsequent cognitive decline. This study investigated whether APOE genotype is related to β-amyloid (Aβ) burden in brain regions preferentially affected by AD and whether Aβ burden is asso...

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Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Mecca, Adam P., Barcelos, Nicole M., Wang, Shuo, Brück, Anna, Nabulsi, Nabeel, Planeta-Wilson, Beata, Nadelmann, Jennifer, Benincasa, Amanda L., Ropchan, Jim, Huang, Yiyun, Gelernter, Joel, Van Ness, Peter H., Carson, Richard E., van Dyck, Christopher H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722236/
https://ncbi.nlm.nih.gov/pubmed/29111487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.09.027
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