Cortical β-Amyloid Burden, Gray Matter, and Memory in Adults at Varying APOE ε4 Risk for Alzheimer’s Disease

Models of preclinical Alzheimer’s disease (AD) propose that cerebral amyloidosis leads to neurodegeneration and subsequent cognitive decline. This study investigated whether APOE genotype is related to β-amyloid (Aβ) burden in brain regions preferentially affected by AD and whether Aβ burden is asso...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Mecca, Adam P., Barcelos, Nicole M., Wang, Shuo, Brück, Anna, Nabulsi, Nabeel, Planeta-Wilson, Beata, Nadelmann, Jennifer, Benincasa, Amanda L., Ropchan, Jim, Huang, Yiyun, Gelernter, Joel, Van Ness, Peter H., Carson, Richard E., van Dyck, Christopher H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722236/
https://ncbi.nlm.nih.gov/pubmed/29111487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.09.027
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